Controversies in the Management of Stage IIIA Non-Small-Cell Lung Cancer

Posted On 2021-05-26 13:56:16


The eighth edition of the tumor-node-metastasis (TNM) classification classified stage III non-small cell lung cancer in sub-stages IIIA, IIIB, and IIIC. There is no further subclassification but Stage IIIA represents already a heterogeneous group of lung cancers invading chest wall/mediastinal organs or with concomitant N2 disease. This heterogeneity poses a tremendous challenge for surgeons, oncologists, radiation-oncologist involved in the management of patients with Stage IIIA disease. This series is a comprehensive overview about management of stage IIIA lung cancer by leading experts internationally recognized.

Editorial
Controversies in the management of stage IIIa non-small-cell lung cancer
Fabrizio Minervini, Marco Scarci

Review Article
Heterogeneity of stage IIIA non-small cell lung cancer—different tumours, different nodal status, different treatment, different prognosis: a narrative review
Dominik V. Flury, Fabrizio Minervini, Gregor J. Kocher

Management of stage IIIA non-small-cell lung cancer: role of surgery
Niki Iranpour, Jacqueline K. Olive, Mara B. Antonoff

Management of stage IIIA non-small cell lung cancer (NSCLC): role of the chemotherapy
Nathalie Baudoux, Alex Friedlaender, Alfredo Addeo

Management of stage IIIA NSCLC: the role of radiotherapy—a narrative review
Thomas Iseli, Krisztian Süveg, Galina Farina Fischer, Markus Glatzer, Paul Martin Putora

Role of immunotherapy in stage IIIA non-small cell lung cancer: a narrative review
Virginia Calvo, Belén Sierra-Rodero, Alberto Cruz-Bermúdez, Mariano Provencio

Stage IIIA non-small cell lung cancer: a contraindication for video-assisted thoracic surgery lobectomy?—a narrative review
Philipp Schnorr, Donatas Zalepugas, Davide Patrini, Joachim Schmidt, Benedetta Bedetti

Management of stage IIIA non-small cell lung cancer in elderly patients: should we do differently?—a narrative review
Fabrizio Minervini, Pietro Bertoglio, Peter Kestenholz, Gregor J. Kocher, Nail Atasayar, Marco Scarci

Narrative review of the management of stage IIIA non-small cell lung cancer: does different management equal different quality of life?
Jason Trevis, Patrick Barclay, Nicholas Marshall, Cecilia Pompili

Editorial Commentary
Persistent N2 disease after neoadjuvant treatment...and now? The oncologist view
Oliver Gautschi, Fabrizio Minervini, Peter Kestenholz

Disclosure:
The series “Controversies in the Management of Stage IIIA Non-Small-Cell Lung Cancer” was commissioned by the editorial office, Current Challenges in Thoracic Surgery without any sponsorship or funding. Fabrizio Minervini and Marco Scarci are serving as the unpaid Guest Editors for the series.