The eighth edition of the tumor-node-metastasis (TNM) classification classified stage III non-small cell lung cancer in sub-stages IIIA, IIIB, and IIIC.
There is no further subclassification but Stage IIIA represents already a heterogeneous group of lung cancers invading chest wall/mediastinal organs or with concomitant N2 disease. Even the involvement of N2 stations includes different subcategories (single-, multi-level, bulky disease).
This heterogeneity poses a tremendous challenge for surgeons, oncologists, radiation-oncologist involved in the management of patients with Stage IIIA disease.
We would like to provide with this series a comprehensive overview about management of stage IIIA lung cancer by leading experts internationally recognized.
Under the assumption that multidisciplinarity should be the key stone in decision making process, we consider this series like a journey between several controversies that so far have not yet been resolved.
Provenance and Peer Review: This article was commissioned by the editorial office, Current Challenges in Thoracic Surgery for the series “Controversies in the Management of Stage IIIA Non-Small-Cell Lung Cancer”. The article did not undergo external peer review.
Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/ccts-21-21). The series “Controversies in the Management of Stage IIIA Non-Small-Cell Lung Cancer” was commissioned by the editorial office without any funding or sponsorship. Fabrizio Minervini served as the unpaid Guest Editor of the series. Marco Scarci served as the unpaid Guest Editor of the series. The authors have no other conflicts of interest to declare.
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